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1

Time-to-event analysis with artificial neural networks: An integrated analytical and rule-based study for breast cancer

Paulo J.G. Lisboa, Terence A. Etchells, Ian H. Jarman, M.S. Hane Aung, Sylvie Chabaud, Thomas Bachelot, David Perol, Thérèse Gargi, Valérie Bourdès, Stéphane Bonnevay, Sylvie Négrier

Journal:

Neural Networks

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

2

Interpreting overall survival results when progression-free survival benefits exist in today's oncology landscape: a metastatic renal cell carcinoma case study

Orjan, Akerborg, Tang, Yiyun, Bycott, Paul, Linus, Jonsson, Sylvie, Negrier, Chen, Connie

Journal:

Cancer Management and Research

Year:

2014

Language:

english

File:

PDF, 389 KB

english, 2014

3

Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial

Brian I Rini, Bernard Escudier, Piotr Tomczak, Andrey Kaprin, Cezary Szczylik, Thomas E Hutson, M Dror Michaelson, Vera A Gorbunova, Martin E Gore, Igor G Rusakov, Sylvie Negrier, Yen-Chuan Ou, Daniel

Journal:

Year:

2011

Language:

english

File:

PDF, 363 KB

english, 2011

4

Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial

Motzer, Robert J, Escudier, Bernard, Tomczak, Piotr, Hutson, Thomas E, Michaelson, M Dror, Negrier, Sylvie, Oudard, Stephane, Gore, Martin E, Tarazi, Jamal, Hariharan, Subramanian, Chen, Connie, Rosbr

Journal:

The Lancet Oncology

Year:

2013

Language:

english

File:

PDF, 316 KB

english, 2013

5

Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma

Motzer, Robert J., Penkov, Konstantin, Haanen, John, Rini, Brian, Albiges, Laurence, Campbell, Matthew T., Venugopal, Balaji, Kollmannsberger, Christian, Negrier, Sylvie, Uemura, Motohide, Lee, Jae L.

Journal:

New England Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 333 KB

english, 2019

6

Bulletin de synthèse de veille 2006

Roland Bugat, François Planchamp, Thierry Lesimple, Jean-Jacques Voigt, Stéphane Culine, Alain Lortholary, Yacine Merrouche, Gérard Ganem, Marie-Christine Kaminsky, Sylvie Négrier, Maurice Pérol, Kari

Journal:

Year:

2007

File:

PDF, 101 KB

2007

7

Annonce du projet thérapeutique en cancérologie. Facteurs influençant la réussite de l'entretien patient-médecin et intérêt d'un deuxième entretien non médical

Sylvie Négrier, Frédéric Gomez, Frank Chauvin, Murielle Buclon, Laurence Syp, Giovanna Gonnon, Arlette Dumortier, Manon Friedrich, Pierre Saltel

Journal:

La Presse Médicale

Year:

2007

File:

PDF, 311 KB

2007

8

Comparison of Artificial Neural Network with Logistic Regression as Classification Models for Variable Selection for Prediction of Breast Cancer Patient Outcomes

Bourdès, Valérie, Bonnevay, Stéphane, Lisboa, Paolo, Defrance, Rémy, Pérol, David, Chabaud, Sylvie, Bachelot, Thomas, Gargi, Thérèse, Négrier, Sylvie

Journal:

Advances in Artificial Neural Systems

Year:

2010

Language:

english

File:

PDF, 3.03 MB

english, 2010

9

Randomized trial of treatment with cisplatin and interleukin-2 either alone or in combination with interferon-α-2a in patients with metastatic melanoma : A Federation Nationale des Centres de Lutte Contre le Cancer Multicenter, parallel study

Thierry Dorval, Sylvie Négrier, Christine Chevreau, Marie-Françoise Avril, Daniel Baume, Didier Cupissol, Ralph Oskam, Ria de Peuter, Jan Vinke, Alain Herrera, Bernard Escudier

Journal:

Year:

1999

Language:

english

File:

PDF, 88 KB

english, 1999

10

Role of interleukin-6 in the paraneoplastic inflammatory syndrome associated with renal-cell carcinoma

Jean-Yves Blay, Jean-François Rossi, John Wijdenes, Christine Menetrier-Caux, Stéphane Schemann, Sylvie Négrier, Thierry Philip, Marie Favrot

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 191 KB

english, 1997

11

Combination of neoadjuvant chemotherapy with cryotherapy and surgical resection for the treatment of unresectable liver metastases from colorectal carcinoma : Long-term results

Michel Rivoire, Franco De Cian, Pierre Meeus, Sylvie Négrier, Henri Sebban, Pierre Kaemmerlen

Journal:

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

12

Subcutaneous interleukin-2 and interferon α in the treatment of patients with metastatic renal cell carcinoma—Less efficacy compared with intravenous interleukin-2 and interferon α : Results of a multicenter Phase II trial from the Groupe Français d'Immunothérapie

Alain Ravaud, Rémy Delva, Fréderic Gomez, Christine Chevreau, Jean-Yves Douillard, Jean Peny, Bruno Coudert, Sylvie Négrier

Journal:

Year:

2002

Language:

english

File:

PDF, 88 KB

english, 2002

13

Prolonged survival after complete resection of metastases from intraocular melanoma

Michel Rivoire, Laurent Kodjikian, Sylvie Négrier

Journal:

Year:

2004

Language:

english

File:

PDF, 65 KB

english, 2004

14

Low serum albumin levels and liver metastasis are powerful prognostic markers for survival in patients with carcinomas of unknown primary site

Pascal Seve, Isabelle Ray-Coquard, Veronique Trillet-Lenoir, Michael Sawyer, John Hanson, Christiane Broussolle, Sylvie Negrier, Charles Dumontet, John R. Mackey

Journal:

Year:

2006

Language:

english

File:

PDF, 190 KB

english, 2006

15

Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis : Results of a randomized controlled trial

Sylvie Negrier, David Perol, Alain Ravaud, Christine Chevreau, Jacques-Olivier Bay, Remy Delva, Emmanuel Sevin, Armelle Caty, Bernard Escudier

Journal:

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

16

REEP1 mutations in SPG31: Frequency, mutational spectrum, and potential association with mitochondrial morpho-functional dysfunction

Cyril Goizet, Christel Depienne, Giovanni Benard, Amir Boukhris, Emeline Mundwiller, Guilhem Solé, Isabelle Coupry, Julie Pilliod, Marie-Laure Martin-Négrier, Estelle Fedirko, Sylvie Forlani, Cécile C

Journal:

Year:

2011

Language:

english

File:

PDF, 589 KB

english, 2011

17

Phase II study of fotemustine as second-line treatment after failure of immunotherapy in metastatic renal cell carcinoma

Christine Lassel, Yacine Merrouche, Sylvie Negrier, Paul Rebattu, Jocelyne Berille, Jean-Pierre Bizzari, Franck Chauvin, Thierry Philip

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 265 KB

english, 1993

18

Phase I clinical and pharmacokinetic study of S9788, a new multidrug-resistance reversal agent given alone and in combination with doxorubicin to patients with advanced solid tumors

Brigitte Tranchand, Gilles Catimel, Catherine Lucas, Marlis Sarkany, Gérard Bastian, Eric Evene, Jean-Paul Guastalla, Sylvie Négrier, Paul Rebattu, Arlette Dumortier, Maurice Foy, François Grossin, Bé

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 222 KB

english, 1998

19

O-Mel-Inib: A Cancéro-pôle Nord-Ouest multicenter phase II trial of high-dose Imatinib mesylate in metastatic uveal melanoma

Nicolas Penel, Corinne Delcambre, Xavier Durando, Stéphanie Clisant, Mohamed Hebbar, Sylvie Negrier, Charles Fournier, Nicolas Isambert, Frédéric Mascarelli, Frédéric Mouriaux

Journal:

Investigational New Drugs

Year:

2008

Language:

english

File:

PDF, 117 KB

english, 2008

20

The medical treatment of metastatic renal cell cancer in the elderly: Position paper of a SIOG Taskforce

Joaquim Bellmunt, Sylvie Négrier, Bernard Escudier, Ahmad Awada, Matti Aapro

Journal:

Critical Reviews in Oncology/Hematology

Year:

2009

Language:

english

File:

PDF, 140 KB

english, 2009

21

Phase I Study of Daily Irinotecan as a Radiation Sensitizer for Locally Advanced Pancreatic Cancer

Christelle de la Fouchardière, Sylvie Négrier, Hugues Labrosse, Isabelle Martel Lafay, Françoise Desseigne, Pierre Méeus, David Tavan, Fabien Petit-Laurent, Michel Rivoire, David Pérol, Christian Carr

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 92 KB

english, 2010

22

Overall survival in patients with metastatic renal cell carcinoma initially treated with bevacizumab plus interferon-α2a and subsequent therapy with tyrosine kinase inhibitors: a retrospective analysis of the phase III AVOREN trial

Sergio Bracarda, Joaquim Bellmunt, Bohuslav Melichar, Sylvie Négrier, Emilio Bajetta, Alain Ravaud, Vesna Sneller, Bernard Escudier

Journal:

BJU International

Year:

2011

Language:

english

File:

PDF, 231 KB

english, 2011

23

Economic evaluation of new targeted therapies for the first-line treatment of patients with metastatic renal cell carcinoma

Ágnes Benedict, Robert A. Figlin, Per Sandström, Ulrika Harmenberg, Anders Ullén, Claudie Charbonneau, Rickard Sandin, Edit Remák, Subramanian Hariharan, Sylvie Négrier

Journal:

BJU International

Year:

2011

Language:

english

File:

PDF, 378 KB

english, 2011

24

Acute renal failure with preserved renal plasma flow induced by cancer immunotherapy

Mercatello, Alain, Hadj-Aïssa, Aoumeur, Négrier, Sylvie, Allaouchiche, Bernard, Coronel, Bernard, Tognet, Eve, Bret, Monique, Favrot, Marie, Pozet, Nicole, Moskovtchenko, Jean-François

Journal:

Kidney International

Year:

1991

Language:

english

File:

PDF, 571 KB

english, 1991

25

Prognostic factors of response or failure of treatment in patients with metastatic renal carcinomas treated by cytokines: a report from the Groupe Français d’Immunothérapie

Sylvie Negrier, Frédéric Gomez, Jean-Yves Douillard, Alain Ravaud, Christine Chevreau, Murielle Buclon, David Perol, Christine Lasset, Bernard Escudier

Journal:

World Journal of Urology

Year:

2005

Language:

english

File:

PDF, 220 KB

english, 2005

26

Treatment of Liver Metastases From Uveal Melanoma

Michel Rivoire, Laurent Kodjikian, Stefano Baldo, Pierre Kaemmerlen, Sylvie Négrier, Jean-Dominique Grange

Journal:

Annals of Surgical Oncology

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

27

Antiangiogenic treatments and mechanisms of action in renal cell carcinoma

Sylvie Négrier, Eric Raymond

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 311 KB

english, 2012

28

Métastases cardiaques et cancers colorectaux : à propos d’un cas

Christelle de la Fouchardière, Françoise Desseigne, Florence Orlandini, Arnaud de la Fouchardière, Sylvie Négrier

Journal:

Gastroentérologie Clinique et Biologique

Year:

2007

Language:

french

File:

PDF, 189 KB

french, 2007

29

Protein chip array profiling analysis of sera from neuroblastoma patients

Valérie Combaret, Christophe Bergeron, Stéphanie Bréjon, Isabelle Iacono, David Perol, Sylvie Négrier, Alain Puisieux

Journal:

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

30

Why don’t cancer patients enter clinical trials? A review

Patrick Castel, Sylvie Négrier, Jean-Pierre Boissel

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

31

Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

Jedd D Wolchok, Bart Neyns, Gerald Linette, Sylvie Negrier, Jose Lutzky, Luc Thomas, William Waterfield, Dirk Schadendorf, Michael Smylie, Troy Guthrie Jr, Jean-Jacques Grob, Jason Chesney, Kevin Chin

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 246 KB

english, 2010

32

Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial

Sylvie Négrier, Gwenaëlle Gravis, David Pérol, Christine Chevreau, Rémy Delva, Jacques-Olivier Bay, Ellen Blanc, Céline Ferlay, Lionnel Geoffrois, Frédéric Rolland, Eric Legouffe, Emmanuel Sevin, Brig

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 236 KB

english, 2011

33

Optimisation of sunitinib therapy in metastatic renal cell carcinoma: adverse-event management

Sylvie Négrier, Alain Ravaud

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 515 KB

english, 2007

34

Case Report 3. Sunitinib malate in patients with cerebellar metastases

Sylvie Négrier

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 839 KB

english, 2007

35

mRCC management: past, present and future

Manuela Schmidinger, Martin Gore, Camillo Porta, Sylvie Négrier, Bernard Escudier

Journal:

European Journal of Cancer Supplements

Year:

2012

Language:

english

File:

PDF, 512 KB

english, 2012

36

Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma

Escudier, Bernard, Eisen, Tim, Stadler, Walter M., Szczylik, Cezary, Oudard, Stéphane, Siebels, Michael, Negrier, Sylvie, Chevreau, Christine, Solska, Ewa, Desai, Apurva A., Rolland, Frédéric, Demkow,

Journal:

Boston Medical and Surgical Journal

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

37

Sorafenib and sunitinib for elderly patients with renal cell carcinoma

Derbel Miled, Olfa, Dionne, Christine, Terret, Catherine, Segura-Ferlay, Céline, Flechon, Aude, Neidhart, Eve-Marie, Negrier, Sylvie, Droz, Jean-Pierre

Journal:

Journal of Geriatric Oncology

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

38

A Phase II Trial of Sunitinib in Patients With Renal Cell Cancer and Untreated Brain Metastases

Chevreau, Christine, Ravaud, Alain, Escudier, Bernard, Amela, Eric, Delva, Remy, Rolland, Frederic, Tosi, Diego, Oudard, Stephane, Blanc, Ellen, Ferlay, Celine, Négrier, Sylvie

Journal:

Clinical Genitourinary Cancer

Year:

2014

Language:

english

File:

PDF, 256 KB

english, 2014

39

Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma

Motzer, Robert J., Hutson, Thomas E., Tomczak, Piotr, Michaelson, M. Dror, Bukowski, Ronald M., Rixe, Olivier, Oudard, Stéphane, Negrier, Sylvie, Szczylik, Cezary, Kim, Sindy T., Chen, Isan, Bycott, P

Journal:

Boston Medical and Surgical Journal

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

40

Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma

Harmon, Charles S., DePrimo, Samuel E., Figlin, Robert A., Hudes, Gary R., Hutson, Thomas E., Michaelson, M. Dror, Négrier, Sylvie, Kim, Sindy T., Huang, Xin, Williams, J. Andrew, Eisen, Tim, Motzer,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

41

Prognostic Factors of Metastatic Renal Cell Carcinoma After Failure of Immunotherapy: New Paradigm From a Large Phase III Trial With Shark Cartilage Extract AE 941

Escudier, Bernard, Choueiri, Toni K., Oudard, Stéphane, Szczylik, Cezary, Négrier, Sylvie, Ravaud, Alain, Chevreau, Christine, Venner, Peter, Champagne, Pierre, Croteau, Daniel, Dupont, Eric, Hariton,

Journal:

The Journal of Urology

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

42

Improvement in Overall Survival of Patients with Advanced Renal Cell Carcinoma: Prognostic Factor Trend Analysis from an International Data Set of Clinical Trials

Patil, Sujata, Manola, Judith, Elson, Paul, Negrier, Sylvie, Escudier, Bernard, Eisen, Tim, Atkins, Michael, Bukowski, Ronald, Motzer, Robert J.

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 735 KB

english, 2012

43

Pharmacokinetics of pazopanib administered in combination with bevacizumab

Imbs, Diane-Charlotte, Négrier, Sylvie, Cassier, Philippe, Hollebecque, Antoine, Varga, Andrea, Blanc, Ellen, Lafont, Thierry, Escudier, Bernard, Soria, Jean-Charles, Pérol, David, Chatelut, Etienne

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

44

Recombinant Human Interleukin-2, Recombinant Human Interferon Alfa-2a, or Both in Metastatic Renal-Cell Carcinoma

Negrier, Sylvie, Escudier, Bernard, Lasset, Christine, Douillard, Jean-Yves, Savary, Jacqueline, Chevreau, Christine, Ravaud, Alain, Mercatello, Alain, Peny, Jean, Mousseau, Mireille, Philip, Thierry,

Journal:

Boston Medical and Surgical Journal

Year:

1998

Language:

english

File:

PDF, 99 KB

english, 1998

45

[IEEE 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Lyon, France (2007.08.22-2007.08.26)] 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Development of a Rule Based Prognostic Tool for HER 2 Positive Breast Cancer Patients

Lisboa, Paulo J.G., Etchells, Terence A., Jarman, Ian H., Aung, M.S. Hane, Chabaud, Sylvie, Bachelot, Thomas, Perol, David, Gargi, Therese, Bourdes, Valerie, Bonnevay, Stephane, Negrier, Sylvie

Year:

2007

Language:

english

File:

PDF, 382 KB

english, 2007

46

Characterizing fatigue associated with sunitinib and its impact on health-related quality of life in patients with metastatic renal cell carcinoma

Cella, David, Davis, Mellar P., Négrier, Sylvie, Figlin, Robert A., Michaelson, M. Dror, Bushmakin, Andrew G., Cappelleri, Joseph C., Sandin, Rickard, Korytowsky, Beata, Charbonneau, Claudie, Matczak,

Journal:

Year:

2014

Language:

english

File:

PDF, 601 KB

english, 2014

47

[IEEE 2007 International Joint Conference on Neural Networks - Orlando, FL, USA (2007.08.12-2007.08.17)] 2007 International Joint Conference on Neural Networks - Time-to-event analysis with artificial neural networks: An integrated analytical and rule-based study for breast cancer

Lisboa, Paulo J.G., Etchells, Terence A., Jarman, Ian H., Aung, M.S. Hane, Chabaud, Sylvie, Bachelot, Thomas, Perol, David, Gargi, Therese, Bourdes, Valerie, Bonnevay, Stephane, Negrier, Sylvie

Year:

2007

Language:

english

File:

PDF, 654 KB

english, 2007

48

Autologous Bone Marrow Transplantation in Pediatric Solid Tumors

Yaniv, Isaac, Bouffet, Eric, Irle, Claude, Negrier, Sylvie, Biron, Pierre, Favrot, Marie, Philip, Irène, Brunat-Mentigny, Maud, Philip, Thierry

Journal:

Pediatric Hematology-Oncology

Year:

1990

Language:

english

File:

PDF, 754 KB

english, 1990

49

Axitinib for the Treatment of Metastatic Renal Cell Carcinoma

Larkin, James, Fishman, Mayer, Wood, Laura, Negrier, Sylvie, Olivier, Kara, Pyle, Linda, Gorbunova, Vera, Jonasch, Eric, Andrews, Lori, Staehler, Michael

Journal:

American Journal of Clinical Oncology

Year:

2014

Language:

english

File:

PDF, 150 KB

english, 2014

50

Irinotecan associated with cetuximab given every 2 weeks versus cetuximab weekly in metastatic colorectal cancer

Mrabti, Hind, Negrier, Sylvie, Errihani, Hassan, la Fouchardiere, Christelle De, Desseigne, Francoise, Dussart, Sophie

Journal:

Journal of Cancer Research and Therapeutics

Year:

2009

Language:

english

File:

PDF, 937 KB

english, 2009